GPU-Accelerated MEP Reconstruction

See Atoms.
Understand Materials.

Atomic Intelligence delivers next-generation MEP (Multislice Electron Ptychography) software and expert data analysis services for atomic-resolution electron microscopy — beyond the limits of conventional TEM labs.

看见原子。
理解材料。

原子智能提供新一代 MEP(多切片电子叠层成像)软件与专业数据分析服务,突破传统透射电镜实验室的极限,实现原子分辨率的定量表征。

100× Faster than CPU
🔬
<1 pm Precision
📐
>100 nm Thickness
🌐
Remote / Cloud Ready

Not a Lab. A Software-Defined Analysis Engine.

Traditional third-party labs like Wintech Nano excel at sample-based FA and material analysis. We complement them with algorithm-driven, atomic-resolution reconstruction that no conventional lab can deliver.

Software

Software-First

No physical lab, no sample shipping. Send your 4D-STEM dataset, get atomic-resolution results remotely.

Atomic

Atomic Precision

Sub-picometer position accuracy vs. nanometer-scale conventional TEM. See individual atomic columns and their displacements.

Thick

Break Thickness Limits

Reconstruct specimens >100 nm thick with atomic precision. Conventional SSB/TEM fails beyond 20–30 nm.

GPU

Real-Time Speed

GPU-accelerated reconstruction in minutes, not days. No lab queue, no instrument scheduling conflicts.

How We Differ from Conventional Labs

We don't replace third-party labs — we unlock capabilities they cannot provide. Here's the side-by-side comparison.

Capability Atomic Intelligence Conventional Lab (e.g., Wintech)
Spatial Resolution Sub-picometer (atomic column) Nanometer to sub-nanometer
Specimen Thickness >100 nm (MEP multislice) <30 nm (conventional TEM)
Analysis Mode Software + Remote data service Physical lab + Sample shipping
Turnaround Time Hours to days (GPU parallel) Days to weeks (lab queue)
Quantitative Output Strain tensor, displacement field, polarization map Morphology, EDS mapping, failure location
Data Format 4D-STEM / Ptychography native SEM / TEM / FIB / EDS / EELS
Use Case Focus Atomic-scale defect physics, interface structure, phase transitions Yield improvement, FA root-cause, reliability testing
Cost Model Software license + Per-dataset service Per-sample testing fee (~¥10K–30K/case)
Best For Research groups, advanced-node FA, DFT-EM validation Production FA, material qualification, reliability certification

MEP Reconstruction Software

High-throughput, GPU-accelerated multislice electron ptychography for atomic-resolution imaging beyond the conventional depth and thickness limits.

Atomic Intelligence — MEP Workstation v2.0
Phase Retrieval
Phase Map
MEP Output
Convergence
Atom Positions
Lattice Map
GPU Reconstruction Active — 3.2 min elapsed

GPU-Accelerated Engine

CUDA-optimized multislice propagation achieving 100× speedup over CPU baselines. Handle large-scale 4D-STEM datasets (512×512×64×64) in minutes, not hours.

A100 / H100 / RTX Pro 6000 Ready
🔬

Break Thickness Limits

Proprietary multi-slice algorithms reconstruct thick specimens (>100 nm) with atomic precision—unreachable by conventional SSB/Wigner distribution methods. Ideal for bulk interfaces and 3D-IC TSV structures.

3D-IC / GAA / CFET Compatible
🎯

Geometric Calibration

Built-in probe aberration correction (C1, C3, C5), scan distortion rectification, and tilt-axis refinement—ensuring quantitative accuracy for every reconstruction. Passes ISO 17025 traceability requirements.

Quantitative / ISO 17025 Traceable
🔧

Fab-Ready Integration

Seamless data pipeline from JEOL ARM / Thermo Fisher Spectra / Nion HERMES. Automated batch processing, metadata preservation, and LIMS-compatible JSON/XML reporting for FA labs.

LIMS / SEMI E142 / SECS-GEM

Compatible TEMs & Detectors

MEP reconstruction requires pixelated detectors and aberration-corrected STEM platforms. Our software natively supports the leading 4D-STEM hardware ecosystem.

Je
JEOL
Japan

ARM Series

Cold-FEG double Cs-corrected STEM with sub-Å probe and highest stability for atomic-resolution 4D-STEM ptychography.

  • ARM200F / ARM300F / JEM-ARM200CF
  • Double Cs corrector (probe + image)
  • Cold FEG, info limit ~0.6 Å
  • High-voltage stability < 0.01 ppm/min
Fully Verified
TF
Thermo Fisher
USA / Netherlands

Spectra / Themis Series

X-FEG / X-CFEG monochromated platforms with X lens corrector. Excellent for low-dose ptychography and EELS-correlated 4D-STEM.

  • Spectra 300 / Themis Z / Themis G2
  • X-FEG or X-CFEG + monochromator
  • X lens probe corrector
  • EELS integration ready
Fully Verified
Ni
Nion
USA

HERMES / UltraSTEM

Ultra-high vacuum cold-field emission STEM with Nion-designed quadrupole-octupole correctors. Best-in-class probe coherence for ptychography.

  • HERMES-100 / UltraSTEM 100MC
  • Cold-field emission, 25 meV energy spread
  • Nion QO corrector (C5-capable)
  • UHV environment, minimal contamination
Fully Verified
Hi
Hitachi
Japan

HF-5000 / HD-2700 Series

Dedicated STEM platforms with probe aberration correction and high-tilt capability. Cost-effective entry point for 4D-STEM ptychography.

  • HF-5000 (200 kV, Cs-corrected)
  • HD-2700 (200 kV, dedicated STEM)
  • High-tilt tomography holder compatible
  • Robust automation for batch acquisition
Beta Support
Fe
FEI / Thermo
Legacy

Titan Themis / Krios G3i

Legacy but widely deployed platforms. With pixelated detector retrofit and probe corrector upgrade, capable of high-quality 4D-STEM ptychography.

  • Titan Themis (S)TEM with DCOR
  • Krios G3i (Cryo-EM, 4D-STEM capable)
  • X-FEG or Schottky emitter
  • Detector retrofit recommended
Retrofit Required
Cu
Custom
Open Hardware

Open-Source / Custom 4D-STEM

Custom-built 4D-STEM setups using open-source scan controllers (e.g., TEM Extensibility Interface) and home-built pixelated detectors. We provide SDK integration support.

  • TEM Extensibility Interface (TEI)
  • Custom scan coil drivers
  • Home-built Medipix/Timepix arrays
  • SDK & API integration available
SDK Integration
📷

EMPAD

Cornell / TechnoSoft

128×128 pixel array, 1M fps, 24-bit dynamic range. The gold standard for 4D-STEM ptychography.

128×128 px 1M fps 24-bit
🔲

Medipix3 / Timepix3

CERN / ASI / Quantum Detectors

Event-driven readout, zero noise, 55 µm pixel pitch. Timepix3 adds TOF capability for energy-resolved 4D-STEM.

256×256 px Event-driven Zero noise
📹

Merlin

Quantum Detectors

Medipix3 ASIC-based, 1.2M fps burst mode, radiation hard. Widely used in materials science 4D-STEM.

256×256 px 1.2M fps Rad-hard
🎬

4D Camera

Berkeley Lab / NCEM

512×512 direct electron detector, 4,000 fps, optimized for 4D-STEM diffraction pattern capture at high speed.

512×512 px 4K fps Direct
🔋

Gatan K3 IS / K2 IS

Gatan / Ametek

Direct detection electron counting. K3 IS supports in-situ 4D-STEM with high DQE and large field of view.

~4K×3K px Counting In-situ
🔭

Direct Electron DE-64

Direct Electron

Large-format direct detection, 64 MP, optimized for low-dose diffraction and large momentum transfer capture.

64 MP Low-dose Large FOV

pnCCD (S65)

PNDetector / HZDR

Split pn-junction CCD, 1,000 fps, radiation tolerant. Excellent for high-energy electron diffraction (MeV range).

264×264 px 1K fps MeV-ready
🌟

Stellaris

ASI / Amsterdam Scientific

Hybrid pixel detector with adaptive gain. Optimized for simultaneous EELS and 4D-STEM acquisition.

Hybrid Adaptive EELS-sync
🔷

ARINA

DECTRIS

Hybrid-pixel electron-counting detector purpose-built for 4D-STEM. Up to 120 kfps with noise-free readout and high dynamic range — ideal for ptychography with dwell times below 10 µs.

192×192 px 120 kfps 30–300 keV Retractable

Data Analysis & Reconstruction Services

From raw 4D-STEM datasets to publication-ready atomic structures — our team handles the full analytical pipeline so you can focus on the science. No lab queue, no instrument downtime.

🔄

MEP Reconstruction

Full ptychographic reconstruction with multislice propagation, including phase retrieval, probe recovery, and depth-sectioning for thick specimens.

  • 4D-STEM dataset preprocessing & denoising
  • Multi-slice phase retrieval (ePIE / rPIE / LSQML)
  • Depth-resolved 3D imaging
  • Probe aberration & scan distortion correction
Starting from ¥3,000 / dataset
📊

Quantitative Analysis

Atomic-column position mapping, strain tensor extraction, displacement field visualization, and octahedral tilt quantification with sub-picometer precision.

  • GPA / peak-finding strain mapping
  • Atomic displacement vector field
  • Octahedral distortion & tilt analysis
  • Polarization topology (skyrmion / vortex)
Starting from ¥5,000 / image
🧪

Simulation & Validation

Multislice image simulation, structure model validation, and DFT-EM joint analysis to confirm experimental interpretations with theoretical ground truth.

  • Multislice STEM simulation (QSTEM / abTEM)
  • Structure model fitting & refinement
  • DFT-EM cross-validation (VASP / QE)
  • Defect configuration testing
Starting from ¥4,000 / model
🎨

Visualization & Reporting

Publication-grade figure preparation, 3D atomic structure rendering, and comprehensive analytical reports with full methodology documentation.

  • Journal-ready figure design (Nature / Science / APL)
  • 3D atomic structure rendering (Blender / OVITO)
  • Pseudo-color / overlay / composite maps
  • Supplementary material & method documentation
Starting from ¥2,000 / figure set
🔧

FA Lab Support

On-demand TEM data analysis for semiconductor failure analysis — defect characterization, interface analysis, and process-induced strain evaluation at the atomic scale.

  • Atomic-scale defect site localization
  • Interface roughness & diffusion mapping
  • Process strain & stress evaluation
  • LIMS-compatible JSON/XML reporting
Enterprise quote Contact us
📚

Training & Consulting

Customized workshops on MEP theory, 4D-STEM experimental design, and data analysis workflows for your research group or FA team.

  • MEP theory & algorithm deep-dive
  • 4D-STEM experimental parameter optimization
  • Software operation & pipeline training
  • Analysis workflow consulting
Starting from ¥800 / hour

Where Atomic Intelligence Shines

Real-world scenarios where conventional labs reach their limits and MEP delivers breakthrough insights.

🔬

3D-IC TSV Interface Analysis

Conventional TEM cannot handle >50 nm thick TSV cross-sections. MEP reconstructs 100+ nm Cu/SiO₂ interfaces at atomic resolution, revealing diffusion barriers and void formation.

3D-IC TSV Hybrid Bonding

GAA / CFET Channel Strain Mapping

Sub-picometer strain tensors across nanosheet stacks. Quantify process-induced strain in 2nm-class devices — critical for mobility engineering and threshold voltage tuning.

GAA CFET 2nm Node
🧲

Ferroelectric Domain Topology

Map polarization vortices, skyrmions, and flux-closure domains in HfO₂-based ferroelectrics. Direct observation of atomic displacements enables predictive device modeling.

FeFET HfO₂ Memory
🔋

Solid-State Battery Interface

Atomic-resolution observation of Li-ion migration paths across solid-electrolyte / cathode interfaces. Identify dendrite nucleation sites and grain boundary defects in LLZO/LCO stacks.

Solid-State Li-ion Energy

Built for Atomic Precision

Our technology stack combines cutting-edge algorithms with high-performance computing to deliver results you can trust.

100×
GPU Speedup
vs CPU baseline
<1 pm
Position Precision
Atomic column tracking
>100 nm
Thickness Range
Multislice propagation
4D-STEM
Native Format
Ptychography ready

How We Work

Transparent, efficient, and collaborative — from first contact to final delivery. No lab queue, no shipping delays.

1

Upload Data

Share your 4D-STEM dataset via secure cloud link. We evaluate data quality and define analysis scope within 24 hours.

2

Get Proposal

Receive a detailed plan with timeline, pricing, and deliverables. No charge if the proposal doesn't meet your needs.

3

GPU Analysis

Our team executes reconstruction and quantitative analysis on GPU clusters. Progress updates every 48 hours.

4

Deliver & Explain

Live walkthrough of results, followed by delivery of figures, source data, and methodology documentation.

About Atomic Intelligence

Atomic Intelligence was founded by a team of electron microscopy experts and HPC software engineers with a shared mission: to make atomic-resolution analysis accessible, fast, and quantitative.

We don't compete with traditional third-party labs like Wintech Nano — we complement them. While they excel at sample-based FA, material qualification, and reliability testing, we unlock the atomic-scale insights that conventional TEM cannot reach: sub-picometer strain tensors, 3D atomic structures in thick specimens, and quantitative polarization maps.

Our clients include leading research groups pushing the frontiers of materials science and semiconductor FA labs at advanced nodes (3nm and below) where atomic precision is no longer optional.

关于原子智能

原子智能由电子显微学专家与高性能计算软件工程师团队创立,共同使命是:让原子分辨率分析变得可及、快速且定量化。

我们不与传统第三方实验室(如胜科纳米)竞争——我们与之互补。它们在样品送检式失效分析、材料认证和可靠性测试方面表现出色,而我们解锁传统透射电镜无法触及的原子尺度洞察:亚皮米级应变张量、厚样品中的三维原子结构、以及定量化极化图。

我们的客户包括推动材料科学前沿的领先研究团队,以及先进制程(3nm 及以下)的半导体失效分析实验室——在这些节点,原子精度不再是可选项,而是必需品。

6+
Years EM Experience
20+
Service Types
<1 pm
Precision
Dr

Lead Scientist

TEM / MEP / 4D-STEM

Sw

Software Lead

CUDA / HPC / Algorithms

Da

Data Team

Analysis / Visualization

Fa

FA Support

Semiconductor / Industry

Start Your Atomic Analysis

Send us your dataset or questions. We typically respond within 24 hours with a preliminary assessment and proposal.

Get in Touch

联系我们

📧

Email

contact@atomic-intelligence.com

💬

WeChat

Scan QR code or search 'AtomicIntelligence'

📍

Location

Hangzhou, China · Remote Worldwide

Response Time

Within 24 hours